45. A eukaryotic cell synthesizes an mRNA molecule where the poly-A tail is normal, but a specific mutation prevents the 5' cap from binding the necessary translation initiation factors. Assuming the mRNA is successfully exported to the cytoplasm, which step of protein synthesis would be most immediately and severely affected? (A) The formation of peptide bonds in the P site would cease, halting elongation. (B) The mRNA would be rapidly degraded by hydrolytic enzymes in the cytoplasm. (C) tRNA molecules would fail to be charged with their corresponding amino acids. (D) Release factors would prematurely bind to the AUG codon, causing early termination. (E) The small ribosomal subunit would fail to bind to the mRNA or scan for the AUG start codon.