【已刪除】69 下列何種 β-adrenoceptor 拮抗劑之排除半衰期（elimination half-life）最短？
(A)bisoprolol
(B)esmolol
(C)nadolol
(D)propranolol

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統計： A(0), B(23), C(3), D(0), E(0) #1323819

詳解 (共 1 筆)

#2987221

B. Esmolol has a rapid distribution half-life of about 2 minutes and an elimination half-life of about 9 minutes

A. Bisoprolol has both lipid- and water-soluble properties.[18][22] It has an approximate half-life of 10–12 hours, and when ingested has high bioavailability (approx. 90%)

C. The half-life of therapeutic doses of nadolol is about 20 to 24 hours

D. Propranolol is a highly lipophilic drug achieving high concentrations in the brain. The duration of action of a single oral dose is longer than the half-life and may be up to 12 hours, if the single dose is high enough (e.g., 80 mg)   

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