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16下列抗黴菌藥物中，何者之作用機轉是抑制β(1-3)glucan，而影響黴菌細..-阿摩線上測驗
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1F Bryan 國三上 (2014/05/20)
Caspofungin is a lipopeptide antifungal drug .It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme -β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal-β-D-glucan synthesis to be approved by the United States FDA. 靜脈注射給藥 治療全身性黴菌感染 |
2F Bryan 國三上 (2014/05/23)
Drug Classes → Anti-infectives → Antifungals → Echinocandins : Caspofungin Echinocandins are a class of antifungal drugs that target the fungal cell wall. They are lipopeptide molecules that noncompetitively inhibit (1,3) beta-d-glucan synthase enzyme. This enzyme forms glucan, a major component of the fungal cell wall therefore by inhibiting its synthesis fungal cell walls are damaged. |