Intracranial epidermoid cysts are uncommon congenital lesions which account for about 1% of all intracranial tumors. They result from inclusion of ectodermal elements during neural tube closure, and typically present in middle age due to mass effect on adjacent structures. Their content, derived from desquamated epithelial cells, mimics CSF on CT and MRI, with the exception of DWI which demonstrates restricted diffusion. Management is surgical and prognosis is good.
Clinical presentation
Signs and symptoms of epidermoid cysts are due to gradual mass effect, with presentation including 4:
headaches: most common
cranial nerve deficits
cerebellar symptoms
seizures
raised intracranial pressure
Recurrent aseptic meningitis is uncommon but recognized.