專技 - 藥劑學(包括生物藥劑學)題庫下載題庫

酸中會溶解?

Polycarbophil absorbs about ten times its own weight of water under acidic conditions, but the swelling ratio markedly increases at above pH 4.0 and reaches 70 times the initial weight under pH-neutral conditions. The swelling of polycarbophil is not affected by non-ionic osmolarity, but by ionic strength, showing a decrease with increase of ionic strength.

(C) 在酸中吸水膨脹。

1. 由divinyl glycol及polyacrylic acid所形成的聚合物。因為結構中有酸所以是會在小腸中溶解 ，但在胃中保持穩定。

2. 可以用於治療腹瀉 (在腸道中造成滲透壓，以吸附多餘的水分，降低腹瀉次數)。