25 Mantle cell lymphoma 最常出現的染色體異常為何？
(A) t(11; 14)
(B) t(9; 22)
(C) t(15; 17)
(D) trisomy 12

答案：A
難度： 非常簡單

	1F PPMTPASS 國三上 (2015/06/30) MCL is a subtype of B-cell lymphoma, due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. MCL cells generally over-express cyclin D1 due to a t(11:14)chromosomal translocation in the DNA. More specifically, the translocation is at t(11;14)(q13;q32). 檢舉
	2F JianYi Jiang 高三下 (2020/06/30) (A) t(11; 14)-Mantle cell lymphoma (B) t(9; 22)-CML/ALL (C) t(15; 17)-AML M3 (D) trisomy 12 B-CLL 檢舉

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