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30 賴先生取自診所的處方如下:astemizole 10 mg po tid、ketoconazole 200 mg po bid,下列何者為藥師判讀此處方時最恰當的評估意見?
(A)兩項藥品皆為 azole 類抗黴菌製劑屬重覆用藥
(B)兩藥品之開方劑量超過一般成人之合理劑量範圍
(C)應注意產生心臟毒性不良反應的可能性
(D)此處方內容合理,無須做任何建議或修改


答案:C
難度: 簡單
最佳解!
clothe86704 高三下 (2017/06/11)
terfenadine和astemizo☆☆...


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張凱越 大三上 (2017/07/21)

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.

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