1.Vioxx and other prescription nonsteroidal anti-inflammatory drugs (NSAIDs) are potent inhibitors ot
the cyclooxygenase-2 (COX-2) enzyme. The inhibitory efficacy of these drugs is decreased in the
presence of high substrate concentrations. These drugs are
(A) allosteric regulators.
(B) prosthetic groups.
(C) feedback inhibitors.
(D) competitive inhibitors.
(E) noncompetitive inhibitors.