19. Choose one wrong description about opioid use:
(A) Acute opiate administration activated opiate receptors in central and peripheral nervous
system.
(B) Protein kinase A (PKA) and CREB were also activated after opiate administration
(C) Repeatedly seeking opioid from other clinicians is a more predictive addiction indicator.
(D) Requesting specific drugs is a more predictive addiction indicator.
(E) Aggressive complaining about needing more drug is a less predictive addiction indicator.