37 下列何種抗糖尿病藥物會造成乳酸中毒的副作用？
(A) Troglitazone
(B) Miglitol
(C) Glipizide
(D) Metformin

答案：D
難度： 簡單

	2F Bryan 國三上 (2014/06/03) Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Its pharmacologic mechanisms of action are different from other classes of oral antihyperglycemic agents. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. 檢舉
	3F 菜餅大三上 (2023/05/15) Lactic acidosis：乳酸中毒。 Phenformin因乳酸中毒太嚴重而下架。檢舉
	4F 菜餅大三上 (2023/05/15) Metformin 副作用：腸胃道問題、Vit B12 缺乏、味覺金屬味、乳酸酸中毒、體重減輕(因為有厭食、噁心嘔吐的副作用)。檢舉

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