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54 用於治療糖尿病之藥物中,下列何者不會促進胰島素分泌?
(A) chlorpropamide
(B) glyburide
(C) repaglinide
(D) metformin


答案:D
難度: 簡單
1F
Bryan 國三上 (2014/05/31)
Drug Classes → Metabolic Agents → Antidiabetic Agents → Meglitinides: repaglinide Meglinitides work by stimulating the pancreas to release insulin in response to a meal. It closes ATP-dependent potassium channels in functioning pancreatic beta cells. This blockade of potassium channels depolarizes the beta cells, which leads to opening of calcium channels resulting in influx of calcium. Increased intracellular calcium induces insulin secretion.
Meglitinides are used in the treatment of Type 2 diabetes...
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2F
Bryan 國三上 (2014/05/31)
Metformin is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function.
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3F
菜餅 大三上 (2023/05/13)

Metformin


機轉: 增加周邊組織對葡萄糖的利用、減少肝臟糖質新生(可降低空腹血糖值)、減少葡萄糖在胃腸道吸收、增加 insulin 受體感受性。 

54 用於治療糖尿病之藥物中,下列何者不會促進胰島素分泌? (A)chlor..-阿摩線上測驗