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66 用柯椏素 (chrysarobin) 治療牛皮癬時,因其組成變異大,可以用下列那一項來取代?
(A) Alizarin
(B) Anthralin
(C) Danthron
(D) Emodin


答案:B
難度: 困難

10
 【站僕】摩檸Morning:有沒有達人來解釋一下?
倒數 4天 ,已有 2 則答案
歐拉拉 高三下 (2019/07/05):

anthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. Adverse effects of anthralin include irritation and discoloration of the skin.


This specific property of the molecule inspired workers to study details of its pharmacology. It is important to consider that the drug is relatively innocuous, yet effective, and systemic side effects have not been observed with this anthralin, in contrast to a wide variety of systemic and topical therapies for psoriasis .

Anthralin is also known as dithranol. It is a main active ingredient in topical skin formulations for the treatment of psoriasis. Various formulations of the drug are available, including solutions, foams, and shampoos . The chemical structure of anthralin allows for dual solubility, permitting the compound to be absorbed well through the epidermis .

Anthralin has also been studied in the treatment of warts, showing promising results . Salicylic acid is frequently added to anthralin to augment the stability of anthralin and to increase its penetration and efficacy .

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菜餅 大三上 (2023/06/29):

Anthralin

適應症 : 頑癢、牛皮癬、錢癬及其他癬菌所致之皮膚病症。

ANTHRALIN (DITHRANOL)的適應症、成分、用量、副作用-KingNet國家網路醫藥
https://www.kingnet.com.tw/medicine/generic?recno=1467619778

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66 用柯椏素(chrysarobin)治療牛皮癬時,因其組成變異大,可以用下列..-阿摩線上測驗