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69 下列何者與 mercaptopurine 有嚴重的交互作用?
(A) Mycophenolate mofetil
(B) Mycophenolate sodium
(C) Allopurinol
(D) Cyclosporine


答案:C
難度: 非常簡單
1F
Swear 幼兒園下 (2015/02/03)
Severe bone marrow suppression and other toxicity have been associated with concomitant use of allopurinol and mercaptopurine (6-MP) or azathioprine. 

Allopurinol inhibition of 6-MP first-pass metabolism via hepatic or intestinal xanthine oxidase, the enzyme that catalyzes the inactivation of 6-MP.

69 下列何者與 mercaptopurine 有嚴重的交互作用? (A) ..-阿摩線上測驗