【第一題,本題佔50%】
請閱讀該文獻的內容並回答問題1-4。
(摘錄自BMC Neurol.2019 Aug 15;19(1):196.)
Background: Recovery of upper limb function in individuals after a stroke remains challenging. Modified constraint-induced
movement therapy (m-CIMT) has strong evidence for increasing the use and recovery of sensorimotor function of the paretic upper
limb. Recent studies have shown that priming with aerobic exercise prior to task-specific training potentiates upper limb recovery in
individuals with stroke. This protocol describes a randomized clinical trial designed to determine whether priming with moderate-high
intensity aerobic exercise prior to m-CIMT will improve the manual dexterity of the paretic upper limb in individuals with chronic
hemiparesis.
Methods: Sixty-two individuals with chronic hemiparesis will be randomized into two groups: Aerobic exercise + m-CIMT or
Stretching + m-CIMT. m-CIMT inctudes 1) restraint of the nonparctic upper limb for 90% of waking hours, 2) intensive task-oriented
raining of the paretic upper limb for 3 hiday for 10 days and 3) behavior interventions for improving treatment adherence. Aerobic
exercise will be conducted on a stationary bicycle at intervals of moderate to high intensity. Participants will be evaluated at baseline,
3, 30, and 90 days postintervention by the following instruments: Motor Activity Log, Nottingham Sensory Assessr ment, Wolf Motor
Function Test, Box and Block Test, Nine-Hole Peg Test, Stroke Specific Quality of Life Scale and three-dimens al kinematics. The
data will be tested for normality and homogeneity. Paramnetric data will be analyzed by two-way ANOVA with repeated meas sures and
Bonferroni's adjustment. For nonparametric data, the Friedman test followed by the Wilcoxon test with Bonferroni's adjustment will
be used to compare the ratings for each group. To compare the groups in each assessment, the Mann-Whitney test will be used.
Discussion: This study will provide valuable infornation about the effect of motor priming for fine upper limb skill improvement in
people with chronic poststroke hemiparesis, bringing new evidence about the association of two therapies commonly used in clinical
practice.
【題組】3.請問此篇研究的方法是如何進行?(10%)