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  Tingling hands, feet, or both is an extremely common and bothersome symptom. Such tingling can sometimes be benign and temporary. For example, it could result from pressure on nerves when your arm is crooked under your head as you fall asleep. Or it could be from pressure on nerves when you cross your legs too long. In either case, the “pins and needles” effect — which is usually painless — is soon relieved by removing the pressure that caused it. 
   26 It also can accompany other symptoms, such as pain, itching, numbness, and muscle wasting. In such cases, tingling may be a sign of nerve damage, which can result from causes as varied as traumatic injuries or repetitive stress injuries, bacterial or viral infections, toxic exposures, and systemic diseases such as diabetes. 
  Such nerve damage is known as peripheral neuropathy because it affects nerves distant from the brain and spinal cord, often in the hands and feet. There are more than 100 different types of peripheral neuropathy. 27 More than 20 million Americans, most of them older adults, are estimated to have peripheral neuropathy. 
   28 In diabetic neuropathy, tingling and other symptoms often first develop in both feet and go up the legs, followed by tingling and other symptoms that affect both hands and go up the arms. About two-thirds of people with diabetes have mild to severe forms of nerve damage. In many cases, these symptoms are the first signs of diabetes. In another 30% of peripheral neuropathy cases, the cause is unknown or “idiopathic.” The remaining 40% of cases have a variety of causes. 
   29 As long as the peripheral nerve cells have not been killed, they have the ability to regenerate. Although no treatments are available for inherited types of peripheral neuropathy, many of the acquired types can be improved with treatment. For example, good blood sugar control in diabetes can slow the progression of diabetic neuropathy; vitamin supplementation can correct peripheral neuropathy in people with vitamin deficiencies. General lifestyle recommendations include maintaining an optimal weight, avoiding exposure to toxins, following a doctor-supervised exercise program, eating a balanced diet, and avoiding or limiting alcohol consumption. 30 In some cases, tingling and other symptoms of peripheral neuropathy may be reduced with prescriptions originally developed for treating seizures and depression. 

(A) In many cases, however, tingling in the hands, feet, or both can be severe, episodic, or chronic.
(B) Over time, peripheral neuropathy can worsen, resulting in decreased mobility and even disability.
(C) About a third of the cases of peripheral neuropathy have a history of tingling in the hands, feet, or both. 

(D) Diabetes is one of the most common causes of peripheral neuropathy, accounting for about 30% of cases. 
(AB) Successful treatment depends on an accurate diagnosis and treatment of the underlying cause of the tingling. 
(AC) Tingling in hands, feet, or both can be cured as neuro-therapeutical technologies advance in the twenty-first century. 
(AD) All these may relieve the tingling and numbness in hands, feet, or both because they will help blood circulation in all parts of our bodies. 
(BC) Recommendations also include quitting smoking, which constricts blood supply to blood vessels supplying nutrients to peripheral nerves.

【題組】29


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謝謝 高三上 (2023/08/21):

將選項 "(A) In many cases, however, tingling in the hands, feet, or both can be severe, episodic, or chronic." 放在該段落前,可以為讀者提供更多有關周邊神經病變的症狀和表現,以及可能的嚴重性。這個選項強調在很多情況下,手部、腳部或兩者的刺痛感可能會是嚴重、間歇性或長期性的。

將選項 "(B) Over time, peripheral neuropathy can worsen, resulting in decreased mobility and even disability." 也放在該段落前,可以進一步說明周邊神經病變可能導致的後果。這個選項強調隨著時間的推移,周邊神經病變可能會惡化,導致行動能力下降甚至可能導致殘疾。

將這兩個選項放在該段落前,可以在談到神經病變的治療前提供更多背景資訊,讓讀者對該疾病的嚴重性和可能的後果有更清晰的了解。

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