複選題30.Which of the following statements is/are TRUE of supercoiling? (A) The relaxed form of DNA is more stable and is therefore the preferred form in the cell. (B) Most organisms maintain their DNA in a slightly overwound state in order to enhance strand separation during transcription and replication. (C) Overwound DNA is in the B form so relaxed DNA has less turns than B-form DNA. (D) Most organisms maintain their DNA in a slightly underwound state in order to compact their DNA. (E) The relaxed form of DNA can only be maintained if the DNA is a closed circle.