1. Which of the following statements about the comparison between RNA and DNA synthesis processes is correct?
(A) During RNA synthesis, RNA polymerase requires the removal of nucleosomes to initiate transcription, whereas DNA replication does not involve nucleosome remodeling.
(B) RNA polymerase does not require proofreading during RNA synthesis, whereas DNA polymerase has 3'-5' exonuclease proofreading activity.
(C) Both RNA and DNA synthesis require the binding of DnaA protein to recognize the initiation site.
(D) RNA synthesis uses only dNTPs (deoxynucleotide triphosphates) as substrates, whereas DNA synthesis utilizes both NTPs (nucleotide triphosphates) and dNTPs as substrates.
(E) Both RNA and DNA synthesis use DNA as a template, and neither process requires any protein-assisted initiation complex formation.

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