10. A 56-year-old man with cryptococcal meningitis is being treated with flucytosine and amphotericin B. Flucytosine is metabolized to 5-flurouracil by fungal cells which inhibits DNA synthesis. The selectivity of flucytosine is due to a lack of which enzyme in mammalian cells?
(A)Cytosine deaminase
(B)N-acetyltransferase
(C)Uracil phosphoribosyl transferase
(D)Thymidylate synthetase

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統計: A(3), B(0), C(1), D(0), E(0) #3224333

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