6. Which of the following statement is NOT correct about immunoglobulin producing B cells?
(A) B cell does not express its immunoglobulin gene unless primed by antigen.
(B) B cells rearrange their immunoglobulin gene during their development.
(C) The VDJ rearrangement creates the diversity of immunoglobulin produced by B cells.
(D) Somatic mutation of immunoglobulin gene is one way to produce high affinity antibody.
(E) B cell anergy is one way to induce tolerance.
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