醫學三：80題 ( 包括內科,家庭醫學科等科目及其相關臨床實例與醫學倫理 )題庫下載題庫

Cisplatin is a potent antitumor agent usually administered in combination with other chemotherapy agents to treat a broad spectrum of malignancies. Cisplatin-induced nephrotoxicity is a dose-limiting side effect, which most commonly is manifested by acute and chronic impairment of renal function. (See 'Clinical manifestations' above.)

The likelihood of cisplatin-induced nephrotoxicity is increased with high peak plasma free platinum concentrations, previous therapy with cisplatin, underlying chronic kidney disease (CKD), and concomitant use of other nephrotoxic agents. (See 'Prevention'...

Cisplatin is a potent antitumor agent usually administered in combination with other chemotherapy agents to treat a broad spectrum of malignancies. Cisplatin-induced nephrotoxicity is a dose-limiting side effect, which most commonly is manifested by acute and chronic impairment of renal function. (See 'Clinical manifestations' above.)

The likelihood of cisplatin-induced nephrotoxicity is increased with high peak plasma free platinum concentrations, previous therapy with cisplatin, underlying chronic kidney disease (CKD), and concomitant use of other nephrotoxic agents. (See 'Prevention' above.)

https://www.uptodate.com/contents/cisplatin-nephrotoxicity?search=cisplatin&source=search_result&selectedTitle=2~148&usage_type=default&display_rank=1#H31