12. Glutamate is metabolically converted to a-ketoglutarate and NH₄⁺ by a process described as:
(A) reductive deamination.
(B) hydrolysis.
(C) transamination.
(D) deamination.
(E) oxidative deamination.

8. In the normal oxidation of an odd chain fatty acid, all of the following would be part of the process except(A) Each odd chain fatty acyl CoA will produce one propionyl-CoA.(B) Propionyl-CoA enters the mitochondria using the carnitine-palmitoyltransferase I system.(C) Propiony1-CoA is converted to methylmalonyi-CoA.(D) Methylmalonyl-CoA is converted to succiny1-CoA.(E) The oxidation of an odd chain fatty acid requires biotin to produce propionyl-CoA.

9. Which of the following is not true regarding ketone bodies?(A) Ketone bodies form during the catabolism of fats.(B) Ketone bodies are an cffective means for weight loss, since the body will excrete them in the urine.(C) The first enzyme used in the production of ketone bodies is thiolase.(D) Ketone bodies are usually an alternative fuel in all tissues.(E) None of the above

10. Regarding the mechanism for the control of the adenylate cyclase, which statement is incorrect?(A) It is a membrane protein.(B) It catalyzes the formation of cAMP using UTP.(C) It is often activated or inhibited by G proteins.(D) Its catalytic product is a second messenger in eukaryotic signal transduction.(E) Adrenaline activates the adenylate cyclase indirectly.

11. Which statement is correct?(A) The biosynthesis of dNTPs uses NTPs as the source.(B) The overall scheme of pyrimidine biosynthesis is the same as purine.(C) The pyrimidine catabolism is first degraded to the nucleobase.(D) The pyrimidine ring is assembled before it is attached to ribose-5-phosphate.(E) Ribonucleotide reductase catalyzes deoxyribose to ribose in all biology.

13. In phosphory1 group transfer reactions, the____of the nucleotide serves as an information symbol, channeling  the nucleotide to appropriate metabolic activities.(A) sugar (B) diphosphate anhydride (C) sugar-phosphate ester(D) base (E) None are true.

14. Which of the following statements about mitochondrial transport systems is correct?(A) Malate-aspartate shuttle: converts cytosolic NADH to mitochondrial FADH2(B) ATP-ADP translocase: transfers ATP and a proton from matrix to cytosol while transferring ADP from cytosol to matrix(C) Glycerophosphate shuttle: converts cytosolic FADH2 to mitochondrial NADH(D) The malate-aspartate shuttle is irreversible while the glycerophosphate shuttle is reversible.(E) None of the above are correct.

15. The enzyme glycogen phosphorylase:(A) catalyzes a cleavage of β(1→4) bonds.(B) catalyzes a hydrolytic cleavage of α(1→4) bonds.(C) is a substrate for a kinase.(D) uses glucose 6-phosphate as a substrate.(E) uses glucose as a substrate.

16. All are characteristics associated with "brown fat" except:(A) high levels of mitochondria rich in cytochromes.(B) presence of uncoupler protein-1, thermogenin, in the mitochondrial inner membrane.(C) energy from oxidation is converted to heat.(D) found in newborns and hibernating animals.(E) All are characteristics.

17. From the abbreviated name of the compound Gal(β1→4)Glc, we know that:(A) C-4 of glucose is joined to C-1 of galactose by a glycosidic bond.(B) the compound is a D-enantiomer.(C) the galactose residue is at the reducing end.(D) the glucose is in its pyranose form.(E) the glucose residue is the β anomer.

18. When a mixture of glucose 6-phosphate and fructose 6-phosphate is incubated with the enzyme phosphohexose isomerase, the final mixture contains twice as much giucose 6-phosphate as fructose 6-phosphate. Which one of the following statements is most nearly correct, when applied to the reaction below? (R = 8.315 J/mol·K 且 T = 298 K) Glucose 6-phosphatefructose 6-phosphate(A)  ΔG'° is +1.7 kJ/mol. (B)  ΔG'° is -1.7 kJ/mol.(C) ΔG'° is incalculably large and negative.(D) ΔG'°is incalculably large and positive. (E)  ΔG'° is zero.