12. Hexokinase has a Km of 0.05 mM for D-glucose and a Km of 1.5 mM for D-fructose. Please choose the correct statement(s) based on this information. I: Hexokinase has a greater affinity for D-fructose than for D-glucose. II: D-fructose is a better substrate for hexokinase than D-glucose. III: It takes less D-glucose for the reaction to reach "half " than D-fructose. IV: Hexokinase has a higher kcat for D-glucose than for D-fructose. (A) II (B)III (C)II, III, IV (D) I, II, III (E)II, III