醫學二：100題 ( 包括生理學,生化學,藥理學,病理學等科目及其臨床相關知識 )題庫下載題庫

Certain fundamental changes in cell physiology contribute to development of the malignant phenotype:

• Self-sufficiency in growth signals (proliferation without external stimuli)

• Insensitivity to growth-inhibitory signals

• Evasion of apoptosis

• Defects in DNA repair

• Limitless replicative potential (related to telomere maintenance)

• Sustained angiogenesis to provide adequate nutrition and waste removal

• Ability to invade and metastasize

• Ability to escape immune recognition and regulatio...

Certain fundamental changes in cell physiology contribute to development of the malignant phenotype:

• Self-sufficiency in growth signals (proliferation without external stimuli)

• Insensitivity to growth-inhibitory signals

• Evasion of apoptosis

• Defects in DNA repair

• Limitless replicative potential (related to telomere maintenance)

• Sustained angiogenesis to provide adequate nutrition and waste removal

• Ability to invade and metastasize

• Ability to escape immune recognition and regulation