13. Adenylosuccinase (adenylosuccinate lyase) catalyzes the reaction to remove ______ after ______ has formed an amide with a carbonyl group in purine biosynthesis.
(A) succinate； glutamate
(B) succinate； aspartate
(C) fumarate； alanine
(D) fumarate； aspartate
(E) alpha-ketoglutarate； glutamate
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