14. 5-fluorouridine is an anticancer drug that inhibit the reaction of a
(A) thymidylate synthase;
(B) dihydrofolate reductase;
(C) DNA polymerase;
(D) Topoisomerase

1. Which one of the followings is the major lipid of cell membrane? (A) Cholesterol; (B) Phospholipids; (C) Terpene; (D) Eicosanoids

2. Which one of the following descriptions about Oleic acid is   incorrect  ? (A) Oleic acid has 18 carbon atoms (B) Oleic acid is a monounsaturated fatty acid (C) Oleic acid has only one carbon-carbon double bond (D) The position of carbon-carbon double bond of oleic acid is between C8 and C9

3. The transport of H2O is dependent on which protein? (A) Aquaporin; (B) SERCA; (C) Flippase; (D) Caveolin

4. Which mechanism is related to the glucose transport by GLUT4? (A) Simple diffusion; (B) Facilitated diffusion; (C) Primary transport; (D) Secondary transport

5. Which one of the followings is related to the production of diacylglycerol (DAG) from the membrane lipids? (A) Phospholipase C; (B) Phospholipase A; (C) Phospholipase D; (D) Phospholipase B

6. There are four levels in protein structure: primary, secondary, tertiary, and quaternary. The α-helix is in what level of protein structure? (A) Primary; (B) Secondary; (C) Tertiary; (D) Quaternary

7. The polyampholyte is an important character of a protein. What solution factor has the greatest effect on this protein property? (A) The temperature; (B) The solubility; (C) The ionic strength; (D) The acid-basic condition

8. Regarding to the structure of amino acids, which following description is incorrect? (A) Methionine has a sulfur-containing side chain (B) Phenylalanine is an aromatic amino acid (C) Serine is an aliphatic amino acid (D) Histidine is a basic amino acid

9. The globular protein folding is a thermodynamical process in physiological condition. Which following force of chemical binding interaction does not involve? (A) Van der Walls interactions; (B) Electrostatic interactions; (C) Hydrogen bonds; (D) Polypeptide bonds

複選題10. Regarding to biosynthesis of a protein in eukaryotes, which following description is correct? (A) The molecule of tRNA functions as a template of genetic information, and the rRNA serves as an anti-codon to synthesize specific amino acid (B) Protein synthesis occurs in the ribosome, via a specific aminoacyl-tRNA synthetase (C) The polypeptide synthesis requires an AUG as a start codon, while no specific termination codon is required. (D) The polypeptide chains undergo post-translational modification in endoplasmic reticulum

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