試題詳解

15. Regarding antidepressant analgesics, which of the following statement is least likely:
(A) According to NNT data in treating postherpetic neuralgia, imipramine has slightly better analgesic effect than oxycodone.
(B) Desipramine (25-300 mg/day, oral) has low potency of anticholinergic effect and sedation.
(C) Fluoxetine (5-40 mg/day, oral) has no anticholinergic and sedative effects.
(D) Venlafaxine is relatively free of muscarinic cholinergic, histaminic and alpha-adrenergic receptor effects.
(E) The analgesic effect of antidepressants in treating neuropathic pain is dependent of its antidepressant action.