試題詳解

17, A single IgG antibody is composed of unique peptide sequences totaling ~600 700 amino acids. Using this estimate, the predicted molecular weight of an antibody protein would be ~70-75 kDa. However, an intact antibody protein has a molecular weight of ~150 kDa. Which statement is CORRECT?
(A) IgG antibodies are produced as dimers of two identical IgG monomers.
(B) Each IgG antibody is a complex of two identical light chains and two identical heavy chains.
(C) IgG antibodies tend to aggregate together during purification, thereby distorting molecular weight estimates.
(D) Each IgG antibody is a complex of four identical polypeptides.
(E) IgG antibodies have many heavier amino acids in them than most other proteins.