醫學三：80題 ( 包括內科,家庭醫學科等科目及其相關臨床實例與醫學倫理 )題庫下載題庫

Yeasts 多表示Candida 或Cryptococcus感染。

The standard initial therapy for Candida meningitis has been amphotericin B combined with flucytosine .

Amphotericin B is used because of its fungicidal activity against almost all Candida species, even though drug levels in the cerebrospinal fluid (CSF) and brain are low.

Flucytosine is added because of its anti-candidal activity and excellent penetration into CSF and brain tissue 

Caspofungin and the other echinocandins do not achieve adequate CSF concentrations to treat Candida meningitis.

Pending evidence of efficacy, the echinocandins shou...

Yeasts 多表示Candida 或Cryptococcus感染。

The standard initial therapy for Candida meningitis has been amphotericin B combined with flucytosine .

Amphotericin B is used because of its fungicidal activity against almost all Candida species, even though drug levels in the cerebrospinal fluid (CSF) and brain are low.

Flucytosine is added because of its anti-candidal activity and excellent penetration into CSF and brain tissue 

Caspofungin and the other echinocandins do not achieve adequate CSF concentrations to treat Candida meningitis.

Pending evidence of efficacy, the echinocandins should not be used for CNS candidiasis.

Cox, Gary M., and Carol A. Kauffman. "Central nervous system infections due to dematiaceous fungi (cerebral phaeohyphomicosis)." UpToDate. www. uptodate. com. Acceso Diciembre (2009).