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6. 以下哪些抗藥性細菌感染可被配對抗生素所治療? (1). Extended spectrum beta-lactamase (ESBL)-producing E.coli: Ertapenem (2). KPC carbapenemase-producing K. pneumoniae: Meropenem (3). VRE: Linezolid (4). MRSA: Daptomycin (5). Carbapenem-resistant Pseudomonas aeruginosa: Tigecycline
(A) (1)+(2)+(3)
(B) (1)+(3)+(4)
(C) (3)+(4)+(5)
(D) (1)+(3)+(4)+(5)
(E) (1)+(3)

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難度： 適中

10
 【站僕】摩檸Morning：有沒有達人來解釋一下?
倒數 3天 ,已有 2 則答案
. 大三上 (2021/09/22):

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For carbapenem-resistant A. baumannii, broad-spectrum tetracyclines (tigecycline and eravacycline) often have in vitro activity. However, high

rates of tigecycline resistance have been reported, and there is no  ublished clinical experience regarding eravacycline therapy for  respiratory tract infections. P. aeruginosa are intrinsically resistant to these two agents.

3個讚
檢舉
1000060369497 大二下 (2023/10/04):

(1). Extended spectrum beta-lactamase (ESBL)-producing E.coli: Ertapenem
→ ESBL菌對1-4代cephalosporins抗藥(體外對cephamycin類可能會有活性，如cefoxitin,flomoxef,cefmetazole等)，所以可以使用Ertapenem(Carbapenem類)做治療
(2). KPC carbapenemase-producing K. pneumoniae: Meropenem
→ Carbapenem類抗藥基因主要包含KPC、OXA、NDM、VIM、IMP，因此帶有KPC基因的菌為carbapenem-resistant，不會用meropenem治療
(3). VRE: Linezolid
→ VRE(Vancomycin-resistant Enterococci)，大部分會選用Daptomycin, Linezolid做治療
(4). MRSA: Daptomycin
→ MRSA可依據感染部位、臨床條件、感受性、社區或院內感染選用Vancomycin,teicoplanin,daptomycin,linezolid,tigecycline,ceftaroline,clindamycin,doxycycline,nemonoxacin
(5). Carbapenem-resistant Pseudomonas aeruginosa: Tigecycline
→老虎(Tigecycline)不玩3P:Pseudomonas aeruginosa,Proteus sp.,Providencia sp.

所以答案選(B)(1)+(3)+(4)

2個讚
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6. 以下哪些抗藥性細菌感染可被配對抗生素所治療? (1). Extended ..-阿摩線上測驗