21.朱先生28歲,因癲癇控制不佳住院,病人拒服口服藥品,預備給與phenytoin sodium針劑。
下列敘述何者錯誤?
(A)此藥可以靜脈注射給與
(B)該藥品為強酸性(pH=4)
(C)肌肉注射容易結晶析出
(D)對注射部位的組織會有刺激性
統計: A(251), B(3025), C(191), D(36), E(0) #626484
詳解 (共 7 筆)
Phenytoin本身為弱酸,因此其弱酸鹽就為強鹼
IM: Avoid IM administration due to severe risk of local tissue destruction and necrosis; use fosphenytoin if IM administration necessary (Boucher 1996; Meek 1999). The manufacturer's labeling includes IM administration; however, in general the IM route should be avoided and should NOT be used for status epilepticus.
rf. Uptodate
phenytoin有口服劑型喔
Dosage Forms: US
Capsule, Oral, as sodium:
Dilantin: 30 mg [contains fd&c yellow #10 (quinoline yellow)]
Dilantin: 100 mg
Phenytek: 200 mg, 300 mg [contains brilliant blue fcf (fd&c blue #1), fd&c blue #1 aluminum lake, fd&c blue #2 aluminum lake, fd&c red #40 aluminum lake, fd&c yellow #10 aluminum lake]
Generic: 100 mg, 200 mg, 300 mg
Solution, Injection, as sodium:
Generic: 50 mg/mL (2 mL, 5 mL)
Suspension, Oral:
Dilantin: 125 mg/5 mL (237 mL) [orange-vanilla flavor]
Generic: 125 mg/5 mL (4 mL, 237 mL)
Tablet Chewable, Oral:
Dilantin Infatabs: 50 mg [scored]
Phenytoin Infatabs: 50 mg [scored; contains fd&c yellow #10 aluminum lake, fd&c yellow #6 aluminum lake, saccharin sodium]
Generic: 50 mg
rf. Uptodate