牙醫學(二)（包括口腔病理學、牙科材料學、口腔微生物學、牙科藥理學等科目及其臨床相關知識）題庫下載題庫

Mucoepidermoid carcinoma is the most common salivary gland malignancy. Because of its highly variable biologic potential, it was originally called mucoepidermoid tumor. 

The pathogenesis of this tumor is uncertain, although radiation exposure may be one risk factor. Published series have reported that 38% to 82% of mucoepidermoid carci- nomas will show a t(11;19) reciprocal translocation, which results in the production of the CRTC1-MAML2 fusion oncogene. This translocation is identified more frequently in low- and intermediate-grade tumors.

出自於 Neville ch 11 page 45...