22. Which one of the following statements is incorrect? (A) A transporter can significantly reduce the for polar compounds and ions across the membrane bilayer. (B) P-type ATPases are sensitive to the phosphate analog vanadate. (C) ATPase, an antiporter for outward 2 Na ions and inward ions, produces the membrane potential of-50 to -70 mV. (D) The multidrug transporter (MDR1), an ABC transporter, is responsible for the drug resistance in certain tumors. (E) Cystic fibrosis is resulted from a defective chloride ion channel.