試題詳解

23. Which of the following statements regarding extracellular vesicles (EVs) is incorrect?
(A) Exosomes and microvesicles both are extracellular vesicles (EVs) but differ in their cellular origin. The exosomes bud off from the cell membrane but MVs have endocytic origin.
(B) EVs contain mRNAs and miRNAs and those EV-associated mRNAs and miRNAs can be functionally transferred to recipient cells.
(C) Tumor cells have been shown to exploit EVs to contribute to their progression by inactivating T lymphocytes or natural killer cells as well as promoting differentiation of regulatory T lymphocytes to suppress immune reactions.
(D)Several pathogenic proteins such as prions and β-amyloid peptides have also been reported to exploit exosomes in order to propagate to other cells.
(E) None is incorrect