A) (B)正確 The diagnosis of CDI is based on a combination of clinical criteria: (1) diarrhea (≥3 unformed stools per 24 h for ≥2 days) with no other recognized cause plus (2) detection of toxin A or B in the stool, detection of toxin-producing C. difficile in the stool by nucleic acid ampli- fication testing (NAAT; e.g., polymerase chain reaction [PCR]) or by culture, or visualization of pseudomembranes in the colon (C)錯誤,因為也可以用檢測toxin A或toxin B或核酸檢測
(D) 正確 Although the mean time to resolution of diarrhea is 2–4 days,the response to metronidazole may be much slower. Treatment should not be deemed a failure until a drug has been given for at least 6 days.
(E)正確 Indicators of severe disease may include leukocytosis (≥15,000 white blood cells/μL) and a creatinine level ≥1.5 times the premorbid value.