27. Which following reaction has a negative free energy physiologically? (A) Glucose 6-phosphate + ADP → Glucose + ATP (B) Fructose 1,6-bisphosphate + ADP → fructose 6-phosphate + ATP (C) 1,3-Bisphosglycerate + ADP → 3-phosphoglycerate + ATP (D) Phosphoenolpyruvate + ADP → pyruvate + ATP (E) Carbonyl phosphate + ADP → CO2 + ATP