29 下列何組藥物,彼此因競爭性與白蛋白(albumin)結合,而影響藥物在體內之分佈?
(A) MAOIs+tyramine
(B) Digoxin+antibiotics
(C) Warfarin+phenobarbital
(D) Phenytoin+valproic acid

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統計: A(9), B(6), C(31), D(266), E(0) #413727

詳解 (共 1 筆)

#985704
 (C) Barbiturates reduce the effects of oral anticoagulants by inducing their hepatic metabolism. 
(D) Valproic acid may increase the pharmacologic effects of phenytoin. The mechanism may be related to displacement of phenytoin from plasma proteins.
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