試題詳解

31. Which of the following statements regarding enzymes and transition states is   true  ?
(A) Stabilization of the transition state must be less than stabilization of ES for catalysis to occur.
(B) The transition state conformation of an enzyme catalyzed reaction is identical to the conformation seen in the uncatalyzed transition state.
(C) Binding of substrate to an enzyme often causes strain, thus promoting transition state formation.
(D) Formation of the transition state always assures that the reaction will proceed to product.
(E) All are true.