50. In the case of a patient with liver cirthosis who also indulges in alcohol consumption, which of the
following physiological states might be observed? Which of the following statements could be correct?
(A) The first step in alcohol metabolism requires pyruvate decarboxylase, and patients may benefit
from additional thiamine supplementation.
(B) The thiazole ring of TPP serves as the functional moiety of the coenzyme, facilitating the binding
and transfer of active aldehyde. These steps do not require ATP.
(C) Alcohol dehydrogenase is present in animal tissues, even though ethanol is not a primary
metabolic product in animal cells.
(D) Acetaldehyde and its metabolite do not pose toxicity to animals.
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