1. Which is incorrect about mRNA vaccine?
(A) The mRNA can be synthesized in vitro using bacteriophage T7 RNA polymerase.
(B) The mRNA contains 5'-cap, 5'-UTR, a coding region and 3'-UTR.
(C) The negative charge of the mRNA should be neutralized by positive charge molecules for delivery.
(D) The mRNA is delivered into the cytosol of cells and translated by the ribosome.
(E) The mRNA will enter nuclei and integrate into chromosomes for long-term expression.