6. In an aqueous solution, protein conformation is determined by two major factors. One is the formation of the maximum number of hydrogen bonds. The other is the:
(A) formation of the maximum number of hydrophilic interactions.
(B)maximization of ionic interactions.
(C) minimization of entropy by the formation of a water solvent shell around the protein.
(D)placement of hydrophobic amino acid residues within the interior of the protein.
(E)placement of polar amino acid residues around the exterior of the protein.