試題詳解

35. Which of the following event is not related to Microglia to develop pain hypersensitivity following peripheral nerve injury?
(A) up-regulated P2X4R expression (P2X4R+)
(B) ATP stimulation in the presence of extracellular Ca2+ causes the P2X4R to open a non-selective cation-permeable channel
(C) p38 mitogen-activated protein kinase mediates further Microglial Signaling
(D) release of Brain-Derived Neurotrophic Factor (BDNF)
(E) all of the above are involved to develop pain hypersensitivity following peripheral nerve injury.