36 吳先生因為車禍住院治療,期間併發綠膿桿菌(Pseudomonasaerug..-阿摩線上測驗
1F Bryan 國三上 (2014/05/05)
Carbapenems are a class of beta-lactam antibiotics. They have broad-spectrum antibacterial activity, being active against many aerobic and anaerobic gram-positive and gram-negative organisms. Carbapenems inhibit bacterial cell wall synthesis by binding to the penicillin binding proteins and interfering with cell wall formation. They are extremely resistant to beta-lactamase enzymes, making them very useful in treating bacterial infections where beta-lactamase is produced that makes other beta-lactam antibiotics ineffective... 查看完整內容 |
2F Camille Hsu 高二下 (2018/07/20)
Carbapenems是β-lactam抗生素中的一類,它與傳統β-lactam抗生素的不同主要在於化學結構式中的β-lactam環內第2及第3位置間比Penicillin多了一個不飽和鍵,且β-lactam環中的硫原子也被碳原子所取代,也因而讓此類抗生素不易被β-lactamase所破壞,臨床上常用的此類抗生素包括了Imipenem/Cilastatin、Meropenem 和Ertapenem,但Ertapenem對綠膿桿菌(Pseudomonas aeruginosa)先天就無效 ref:Meropenem 與 Imipenem/Cilastatin 的臨床治療與使用時機 中興醫院 一般內科 蔡正堅 醫師 |