36.以下何種藥品與rifampin併用時,較不可能產生具臨床意義的藥品交互作用..-阿摩線上測驗
2F Bonnie 大一下 (2019/06/18)
Serum itraconazole and ketoconazole concentrations were reduced as much as 90% (often to undetectable values) in patients also receiving rifampin (plus isoniazid in some), and disease relapses have been reported.1,2,3,4,5,6 Rifampin (600mg daily) reduced voriconazole maximum plasma concentration (Cmax) by 93% and AUC by 96% when administered together with voriconazole (200mg every 12 hours) in healthy subjects.7 Rifabutin (300mg daily) had a similar effect when combined with voriconazole, reducing Cmax by 69% and AUC by 78%.7Fluconazole (200mg daily) AUC was decreased an average of 23% aft... 查看完整內容 |
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