試題詳解

37. You are studying the function of a recently identified gene in C. elegans. You have been performing genetic screens for several months in an attempt to isolate loss-of-function mutations in this gene, but unfortunately you have been unsuccessful. Your advisor suggests that you try another approach to eliminate gene function. Which of the following techniques would accomplish this goal?
(A) Design a repressor to bind to the operon of this gene.
(B) Use a histone deacetylase to induce a transcriptionally inactive state.
(C) Use RNA interference to prevent mRNA translation.
(D) Use a wild type strain and mutagenize it with a UV light.
(E) Use antisense DNA to block RNA transcription.