38. Which of the following reaction is most likely catalyzed by an "lyase"?
(A) A + B → C + D
(B) AB + C → A + B
(C) A + H₂O → B + C
(D) A → B
(E) A + ATP → A-PO₄ + ADP

39. On a double-reciprocal plot of Michaelis-Menton equation, the Y-intercept of the line is: (A) (B) (C)(D) (E)

40. You are trying to characterize the kinetic properties of a newly identified enzyme. Which is the most reasonable first kinetic plot to obtain? (Abbreviation used: total enzyme concentration (); substrate concentration ([S]); concentration of enzyme-substrate complex ([ES]); initial velocity ; time (T)) (A) plot vs [ET] (B) plot vs [ES] (C) plot vs [S] (D) plot vs T (E) plot vs 1/T

41. Which peptide sequences can facilitate cells spread in Integrin-dependent manner? (A) sehradısal (B) sehraelsal (C) sehrgdlsal (D) sehkgelsal (E) none of the above

42. Which is not a correct description for N-link glycosylations? (A) The attach site in the protein core is Asn (B) Direct the protein traffic from ER to Golgi (C) The major protein sorting pathway for secreted proteins (D) Involved in protein sorting to lysosomal compartment (E) Sensitive to glycosidase H treatment

43. Which of the following statements is true regarding the polysaccharides starch, glycogen, cellulose, and chitin? (A) All have 1-4 linkages. (B) Starch is built from a different monomer than are the others. (C) Only chitin has a core protein. (D) Each is built from a single type of monomer. (E) Chitin and cellulose differ from each other only in the extent of their branching.

44. Which of the following best supports the endosymbiotic theory of the evolutionary origin of mitochondria? (A) Mitochondria, chloroplasts, and prokaryotes contain electron carriers. (B) Mitochondrial and bacterial ribosomal functions are inhibited by the same antibiotics. (C) Genes for mitochondrial pyruvate dehydrogenase subunits are found in the nuclear DNA. (D) The outer mitochondrial membrane contains the protein porin. (E) Many mitochondrial proteins are imported across both inner and outer membranes after translation on cytoplasmic ribosomes is completed.

45. Which protein is not a component of the basal membrane? (A) type 4 collagen (B) fibronectin (C) nidogen (D) proteoglycan (E) lamin

46. According to the system of enzyme nomenclature developed by the International Union of Biochemists, enzymes that catalyze cleavage of C-C, C-O, C-N and other covalent bonds by atom elimination and often generating double bonds are: (A) Oxidoreductases (B) Hydrolases (C) Lyases (D) Isomerases (E) Ligases.

47. Which one of the following reactions is   NOT   catalyzed by an epimerase? (A) Ribulose 5-phosphate ↔ Xylulose 5-phosphate (B) UDP-Gal → UDPGIc (C) N-Acetyl-glucosamine 6-phosphate → N-Acetyl-mannosamine 6-phosphate (D) Glucose 1-phosphate ↔ Glucose 6-phosphate (E) All are catalyzed by an epimerase.

48. In the urea cycle, which one of the following enzymes is in the matrix of liver mitochondria to catalyze reactions? (A) Carbamoyl phosphate synthase I (B) Argininosuccinate synthase (C) Argininosuccinate lyase (D) Arginase (E) All of them.

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