4 下列物質何者是GABA-Aantagonist? (A)Bicuculli..-阿摩線上測驗
1F 敲敲門 高一下 (2022/01/10)
GABA-A antagonist:Bicuculline,Picrotoxin a number of compounds can bind to the GABAA receptor and antagonize the actions of GABA. Bicuculline, by binding to the GABA recognition site and preventing GABA from binding, produces convulsions in experimental animals . Picrotoxin, via its active metabolite picrotoxinin binds in the Cl-channel to prevent ion flow when the receptor is activated by GABA.Picrotoxin does not alter GABA binding, but instead prevents ion sfrom flowing and is a potent convulsant. Beclofen:GABA-B agonist Muscimol:GABA-A agonist 查看完整內容 |