試題詳解

40. Regarding Central Nervous System Mechanisms of Pain Modulation, which of the following statement is least likely:
(A) Pain-modulating systems involve a network with major relays in the midbrain periaqueductal gray and rostral ventrolateral medulla.
(B) This network exerts bidirectional control over dorsal horn nociceptive transmission by means of separate anti- and pro-nociceptive output from the RVM.
(C) The PAG–RVM system is the central substrate for the actions of opioid and non-opioid analgesic drugs.
(D) The PAG–RVM system receives direct and indirect input from nociceptive transmission pathways to modulate nociception.
(E) It strongly links with the hypothalamus and limbic forebrain , through which cognitive and emotional factors can regulate pain processing.