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Ampicillin Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc.Ampicillin也是有抗G(-)，Ampicillin本來就是IV
Pyelonephritis, Acute, Uncomplicated

PATHOGENS

Like uncomplicated cystitis, the vast majority of acute uncomplicated pyelonephritis (AUP) is caused by E. coli (75-9...

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Ampicillin

1. Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
2. For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc.

Ampicillin也是有抗G(-)，Ampicillin本來就是IV

Pyelonephritis, Acute, Uncomplicated

PATHOGENS

Like uncomplicated cystitis, the vast majority of acute uncomplicated pyelonephritis (AUP) is caused by E. coli (75-95%).

Additional pathogens include other Enterobacteriaceae (e.g., Klebsiellaspp.) and S. saprophyticus.

Proteus spp. can cause pyelonephritis; repeated episodes with this pathogen should raise concern for struvite stones.

S. agalactiae and Enterococcus spp. are possible but uncommon pathogens.S. aureus is an uncommon pathogen and should raise concern for other infectious process (e.g., blood stream infection, endocarditis).

非複雜性急性腎盂腎炎用到Ampicillin的時機

Suspected or proven Enterococcus spp. infection: ampicillin 2 g IV q4h plus aminoglycoside (e.g., gentamicin 5 mg/kg IV daily) for initial therapy, then complete 10-14 d therapy with amoxicillin if susceptible.