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65 Azathioprine 與 allopurinol 的藥品交互作用之成因係共用下列何種酵素?
(A) Hypoxantine-guanine phosphoribosyltransferase(HGPRT)
(B) Xanthine oxidase
(C) Phophoribosyl-1 pyrophosphate(PRPP)synthetase
(D) Cytochrome P 450 3A4


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難度: 非常簡單
1F
粗暴言論duck不必 大一上 (2022/05/31)
The concomitant administration of allopurinol and azathioprine or mercaptopurine requires a dose reduction to one-third to one-fourth of the usual dose of the thiopurine because concomitant administration could increase plasma concentrations of these thiopurines, resulting in severe toxicity.
reference: uptodate

65Azathioprine 與 allopurinol 的藥品交互作用之成因係..-阿摩線上測驗