42. The natural history of chronic HBV infection is divided into 3 phases: immune
tolerance phase, immune clearance phase and viral integration phase. Which of the
following description of viral integration phase is correct?
(A) The serum HBV DNA level is still high
(B) The liver inflammation is usually mild or already cirrhotic
(C) HBsAg becomes negative
(D) HBcAg is usually positive